How does a tuple differ from a list in Python?

A tuple is defined as an immutable collection, which means that once it is created, the elements within a tuple cannot be changed, added, or removed. This characteristic makes tuples particularly useful in situations where a fixed set of values is needed, ensuring that data remains constant throughout the program. For example, tuples can be utilized for representing coordinates in a 2D space since the values seldom change.

On the other hand, lists are mutable, allowing for modifications after their creation. This means that you can easily add, remove, or alter elements in a list. The distinction between mutability and immutability is significant in programming, as it influences how data structures can be used and what operations can be performed on them.

Overall, understanding this key difference helps students recognize when to use tuples for fixed collections of items versus lists for collections that require flexibility in data manipulation.